11/21/2023 0 Comments Alcohol overdose treatment antidoteKim, Michael’s nurse, assesses his neurologic status and monitors his vital signs. Michael is transferred to an in-hospital unit. Differential diagnosis includes ethanol, ethylene glycol, and methanol toxicity, as well as alcoholic ketoacidosis. She orders a bolus of normal saline to help clear the toxins through the kidneys, oral potassium replacement to restore Michael’s electrolyte balance, and supportive care, including lorazepam as needed to minimize alcohol withdrawal symptoms and thiamine to prevent Wernicke’s encephalopathy. Michael’s provider suspects toxic ingestion. Initial laboratory results reveal elevated ethanol 300 mg/dL (normal < 5) and anion gap 20 mmol/L (normal 3-12), and low potassium 3.0 mmol/L (normal 3.5-5.0). His vital signs are heart rate (HR) 124 beats per minute (bpm), blood pressure (BP) 123/74 mmHg, respiratory rate (RR) 14 breaths/minute, and temperature 97.9☏ (36.6☌). Michael has a history of polysubstance abuse (alcohol and cocaine). He’s mildly intoxicated, with a slight hand tremor. Michael Jansen*, age 20, arrives in the emergency department and says he’s been drinking hand sanitizer.
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